Reign of Cthulhu

About this board game

Pandemic: Reign of Cthulhu is a horror-themed game for 2–4 players that takes about 40 minutes to play. Players become investigators working to seal portals and stop ancient evil from breaking into the world.

Built around classic Pandemic gameplay, this unsettling adventure replaces disease-fighting with a struggle against Old Ones, beings of cosmic power whose awakening threatens everything humanity knows. Twelve Old Ones stand ready to unleash unique powers, creating an escalating battle against chaos and madness.

Investigators must find and seal every portal before monsters of unspeakable horror pour into the world. They must also shut down cults while managing the danger of losing their own minds to insanity. Every decision brings the investigators closer to safety—or deeper into the evil lurking beneath their feet.

The game unfolds across fictional New England towns associated with the Cthulhu mythos:

• Arkham
• Dunwich
• Innsmouth
• Kingsport

Rather than curing diseases as in the original Pandemic, players face portals, cults, monsters, and the awakening threat of the Old Ones. The goal remains urgent: seal every portal in time, before the world is destroyed by chaos and the investigators lose themselves to madness.

Part of the Pandemic series, Pandemic: Reign of Cthulhu combines familiar gameplay with a distinctive supernatural horror setting. Its tense race against twelve otherworldly powers offers a dramatic challenge for groups ready to confront the darkness together.